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PeptizydeT (pronounced "Pep-ta-zyde") is a combination of three different proteolytic enzymes isolated from plant sources. Each enzyme has a unique set of peptide bonds it prefers to break, so the combination of these enzymes allows much more efficient means of quickly and thoroughly breaking down (hydrolyzing) proteins to its smaller components. The enzymes in PeptizydeT work only on food proteins, not carbohydrates, fats, or other compounds, and do not interfere with medications or other supplements (unless they are also proteins, which is extremely unlikely). Peptizyde may be used in combination with other enzyme products.
The aminopeptidase enzyme dipeptidyl peptidase IV, or DPP IV, is able to hydrolyze and inactivate the exorphin peptide, casomorphin. However, for maximal protein breakdown, it should be combined with other proteases with different and less stringent peptide bond specificity. For this reason, PeptizydeT also contains papain (from papaya) and another fungal protease with high activity in acid conditions. These enzymes are present in PeptizydeT in high amounts for the purpose of quickly hydrolyzing proteins while the food is still in the stomach. The ability of PeptizydeT enzymes to withstand the low pH of the stomach and remain active under acidic conditions allows hydrolysis of casein and gluten prior to entrance into the small intestine. Casein and gluten, in the presence of pancreatic enzymes in the duodenum, can produce exorphin peptides that may be readily absorbed from the intestine (these peptides are not absorbed from the stomach). PeptizydeT supplements the "normal" hydrolysis of casein, gluten, and other food proteins such that the exorphin peptides are not produced because the specific cleavage pattern to produce these peptides is altered.
PeptizydeT is different from other enzyme products in that it contains only those enzymes needed for protein hydrolysis. No other enzymes have been added. This allows parents to customize enzyme supplementation to the specific needs of their child. Another advantage to this approach is that less potential exists for intolerance reactions due to additional and perhaps unnecessary enzyme proteins. Also, by using only three enzyme blends in PeptizydeT, larger amounts of each enzyme can be added per capsule, insuring that more hydrolysis of food protein can take place in the short time that food is in the stomach.
PeptizydeT is also different in that it has allowed many families to safely modify or even abandon the gluten-free, casein-free (GFCF) diet, thus allowing families more choice in foods available, better nutrition (by re-incorporating important protein sources back into the family diet), and much less stress and worry from fear of food reactions.
One other important difference between PeptizydeT and other products is the scientist who developed the product. Devin Houston, Ph.D. is the owner and creator of all Houston Nutraceutical products. Dr. Houston's experience in and knowledge of enzymes, nutrition, and human biochemistry helped develop a product that is now enabling many families to live better and healthier.
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